A Review Of mif

specified its important position in immunity, It is far from shocking that extra MIF expression has long been linked to exaggerated inflammation and immunopathology. Also, MIF demonstrates effectively-documented proliferative Qualities. MIF is secreted by many different types of cells and interacts with various receptors, which can help to explain the variety of Organic features. Receptors that interact that bind MIF incorporate CD74, and chemokine receptors CXCR2 and CXCR4 (7–fifteen).

A quickly escalating level of literature check here signifies that MIF is implicated from the pathogenesis of sepsis, and inflammatory and autoimmune diseases, suggesting that MIF-directed therapies could possibly present new procedure opportunities for human conditions Sooner or later.

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